Protocol
Montero-Odasso, M., Almeida, Q. J., Burhan, A. M., Camicioli, R., Doyon, J., Fraser, S., Li, K., Liu-Ambrose, T., Middleton, L., Muir-Hunter, S., McIlroy, W., Morais, J. A., Pieruccini-Faria, F., Shoemaker, K., Speechley, M., Vasudev, A., Zou, G. Y., Berryman, N., Lussier, M., … Bherer, L. (2018). SYNERGIC trial (synchronizing exercises, remedies in gait and cognition) a multi-centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. BMC Geriatrics, 18(1). https://doi.org/10.1186/s12877-018-0782-7
Main Results
Bray, N. W., Pieruccini-Faria, F., Witt, S. T., Bartha, R., Doherty, T. J., Nagamatsu, L. S., Almeida, Q. J., Liu-Ambrose, T., Middleton, L. E., Bherer, L., & Montero-Odasso, M. (2023). Combining exercise with cognitive training and vitamin D3 to improve functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI). results from the SYNERGIC trial. GeroScience, 45(3), 1967–1985. https://doi.org/10.1007/s11357-023-00805-6
Bray, N. W., Pieruccini-Faria, F., Witt, S. T., Rockwood, K., Bartha, R., Doherty, T. J., Nagamatsu, L. S., Almeida, Q. J., Liu-Ambrose, T., Middleton, L. E., Bherer, L., & Montero-Odasso, M. (2022). Frailty and functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI): Baseline results from the SYNERGIC trial. GeroScience, 45(2), 1033–1048. https://doi.org/10.1007/s11357-022-00702-4
Montero-Odasso, M., Zou, G., Speechley, M., Almeida, Q. J., Liu-Ambrose, T., Middleton, L. E., Camicioli, R., Bray, N. W., Li, K. Z., Fraser, S., Pieruccini-Faria, F., Berryman, N., Lussier, M., Shoemaker, J. K., Son, S., Bherer, L., McFadyen, B. J., Barha, C., & McGibbon, C. (2023). Effects of exercise alone or combined with cognitive training and vitamin D supplementation to improve cognition in adults with mild cognitive impairment. JAMA Network Open, 6(7). https://doi.org/10.1001/jamanetworkopen.2023.24465